The Life Sciences Center is located on the south side of campus, perpendicular to the Roy Nutt Mathematics, Engineering, and Computer Science Center. The building houses the biology, psychology, and neuroscience departments and contains classroom, teaching labs, research labs, and a green house.

Boardman Hall served as the College's Life Sciences (then-called Natural History) building for 70 years, beginning in 1900. By the mid-1960s, however, it was apparent that its early 20th century facilities, Natural History Museum, and space was not adequate for developing biology and life sciences departments. In fact, as early as the 1930s, a new science building was a known need. President Ogilby mentioned in his 1934-1935 annual report that Boardman Hall was already “crowded from garret to cellar…we have no adequate facilities for research in either of these important departments.”

Under President Albert Jacobs, construction on the Jacobs Life Sciences Center began in 1966. The building was part of a larger initiative under Jacobs' presidency to expand the college's infrastructure, as well as to “increase man's knowledge” of biology and psychology.

When the building was completed in 1968, Jacobs placed a sealed box time in a cornerstone. The box was not to be opened until 2073 and was filled with college memorabilia as well as a letter written by Jacobs to the future President of the College.

The Trinity Tripod, 04/09/1968.

Trinity Alumni Magazine, Spring 1968.

Trinity College Bulletin, Report of the Treasurer 1965-1966.

The Trinity Tripod: 'To Go Further and Faster' College Must Build, 10/13/1964

Trinity College Bulletin (1934-1935), President's Report.